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Maria Spies
B.S., 1994
- Department of Biophysics,
Faculty of Physics and Mechanics, St. Petersburg State Technical
University
Masters of
Technical Sciences, Physics (Specialization in Biophysics), 1996 -
Department of Biophysics, Faculty of Physics and Mechanics, St. Petersburg
State Technical University, and Department of Molecular and Radiation
Biophysics, Petersburg Nuclear Physics Institute, Russian Academy of
Sciences
Ph. D., Biology,
2000 - Department of Biology, Graduate School of Science, Osaka
University, Japan
Postdoctoral Fellow, 2000-2005 -
University of California, Davis, CA |
| |
Current address:
Associate Professor
Carver College of Medicine
University of Iowa
Biochemistry
51 Newton Road, 4-532 BSB
Iowa City, IA 52242
Tel: (319) 335-3221
FAX: (319) 335-9570
maria-spies@uiowa.edu |
Spies, M.,
Dillingham, M.S.,
and
Kowalczykowski, S.C.
(2003).
DNA helicases.
In “McGraw-Hill Yearbook of Science & Technology”, New York, N. Y.,
95-98 [PDF]
[scanned-PDF] [Page proof]
Dillingham, M.S.,
Spies, M., and
Kowalczykowski, S.C.
(2003)
RecBCD enzyme is a bipolar DNA helicase.
Nature,
423, 893 - 897. PMID:
12815438.
[Abstract]
[Full
Text] [PDF]
[Supplementary Figure]
[Supplementary Figure Legend and Methods]
(see News & Views in
Nature Structural Biology 10, 499 -
500 (2003)
[Full
Text] [PDF])
(see Highlight in Nature Reviews Molecular
Cell Biology 4, 513 (2003);
doi:10.1038/nrm1162.
[Full Text]
[PDF])
(Must Read
paper by Faculty of 1000
[Full Text])
(see News &
Information
at UC Davis News Service
[Full Text]
[Printable Version])
Spies, M.,
Bianco, P.R., Dillingham, M.S.,
Handa, N.,
Baskin, R.J.,
and
Kowalczykowski, S.C.
(2003)
A molecular throttle: The recombination hotspot
c
controls DNA translocation by the RecBCD helicase.
Cell, 114, 647-654. PMID:
13678587.
[Abstract]
[Full
Text] [PDF]
[Featured Article]
[Supplemental Table S1]
[Supplemental Table S2]
[Supplemental Table S3]
[Supplemental Movie S1]
[Supplemental Movie S2]
[Supplemental Movie S3]
(see
News & Features at
Bio.com
[Full Text]
[PDF])
(see News &
Information
at UC Davis News Service
[Full Text]
[Printable Version])
(see
News &
Information
at UC Davis News Service
[Full Text]
[Printable Version])
Spies, M. and
Kowalczykowski, S.C.
(2005).
Homologous recombination by the RecBCD and RecF pathways.
In “The Bacterial Chromosome”, N.P. Higgins, ed., (ASM Press,
Washington, D.C.), 389-403.
[PDF]
[Preprint]
Spies, M.,
Dillingham, M.S.,
and
Kowalczykowski, S.C.
(2005)
DNA helicases.
In “McGraw-Hill Encyclopedia of Science & Technology”, New York,
N. Y. [Preprint]
Spies, M.,
Dillingham, M.S.,
and
Kowalczykowski, S.C.
(2005).
Translocation by the RecB motor is
an absolute requirement for {chi}-recognition and RecA protein loading by RecBCD
enzyme.
J. Biol. Chem., 280, 37078 – 37087 (published online July 22, 2005 as
10.1074/jbc.M505520200). PMID: 16041060.
[Abstract]
[Full
Text] [PDF]
Spies, M. and
Kowalczykowski,
S.C.
(2006)
The RecA-binding locus of RecBCD enzyme defines a generalized domain
for recruitment of DNA strand exchange proteins.
Mol. Cell,
21,
573-580. PMID: 16483938.
[Abstract]
[Full
Text] [PDF]
[Supplemental Data]
Spies, M.,
Amitani,
I.,
Baskin, R.J., and
Kowalczykowski,
S.C.
(2007)
RecBCD enzyme switches lead motor subunits in response to
c-recognition.
Cell, 131, 16, 694-705
(doi:10.1016/j.cell.2007.9.023). PMID: 18022364. PMCID: PMC2151923.
[Abstract]
[Full
Text] [PDF] [Supplemental
Data]
(see Cell "RecBCD:
The Supercar of DNA Repair"
[PDF])
(see Egghead Blog about research at UC Davis:
A DNA machine running on two engines
[PDF]) |
