Rad, B. and Kowalczykowski, S.C. (2012)
Efficient Coupling of ATP Hydrolysis to Translocation by RecQ Helicase.
Proc. Natl. Acad. Sci. U.S.A., 109, 1443-1448 (published January 17, 2012, 10.1073/pnas.1119952109). PMID: 22307597; PMCID: PMC3277138 [Abstract] [Full Text] [PDF] [Supporting Information]

Forget, A.L. and Kowalczykowski, S.C. (2012)
Single-molecule imaging of DNA pairing by RecA reveals a three-dimensional homology search.
Nature, 482, 423–427 (published online February 8, 2012, doi:10.1038/nature10782). PMID: 22318518; PMCID: PMC3288143 [Abstract] [Full Text] [PDF] [Supplementary Information] [Supplementary Movie 1] [Supplementary Movie 2] [Supplementary Movie 3]
(see Biocompare, Life Sciences Articles, News: How DNA finds its match [PDF])
(see biotic-blog: How DNA finds its match [PDF])
(see California Aggie: Protein plays DNA matchmaker role [PDF])
(see Cancer-z blogspot: How DNA finds its match [PDF])
(see Cell.com News: UC Davis study shows how DNA finds its match [PDF])
(see Crop Biotech Update: How DNA finds its match [PDF])
(see Current Biology Dispatch: Homologous Recombination: How RecA Finds the Perfect Partner [PDF])
(see EurekAlert: How DNA finds its match [PDF])
(see InvestigaMedicina.com: El proceso de recombinación ha sido una incógnita desde el descubrimiento del ADN [PDF])
(see National Cancer Institute News: UC Davis study shows how DNA finds its match [PDF])
(see Nikon Instruments Research Papers: New insights into DNA repair  [PDF])
(see Phys.Org News: Study shows how DNA finds its match [PDF])
(see ScienceDaily: How DNA finds it match [PDF])
(see UC Davis News and Information: How DNA finds its match [PDF])
(see YouTube video: Scientists show DNA matchup [Video])

Rad, B. and Kowalczykowski, S.C. (2012)
Translocation of E. coli RecQ helicase on single-stranded DNA.
Biochemistry, 51, 2921-2929 (published online March 21, 2012). PMID: 22409300; PMCID: PMC3330151 [Abstract] [Full Text] [PDF]

Handa, N., Yang, L., Dillingham, M. S., Kobayashi, I., Wigley, D.B., and Kowalczykowski, S.C. (2012)
Molecular determinants responsible for recognition of the single-stranded DNA regulatory sequence, χ, by RecBCD enzyme.
Proc. Natl. Acad. Sci. U.S.A., 109, 8901-8906 (published online 17 May 2012, 10.1073/pnas.1206076109). PMID: 22603794; PMCID: PMC3384139 [Abstract] [Full Text] [PDF] [Supporting Information]

Yang, L., Handa, N., Liu, B., Dillingham, M. S., Wigley, D.B., and Kowalczykowski, S.C. (2012)
Alteration of χ recognition by RecBCD reveals a regulated molecular latch and suggests a channel-bypass mechanism for biological control.
Proc. Natl. Acad. Sci. U.S.A., 109, 8907-8912 (published online 17 May 2012, 10.1073/pnas.1206081109). PMID: 22603793; PMCID: PMC3384165  [Abstract] [Full Text] [PDF] [Supporting Information]

Ciccia, A., Nimonkar, A.V., Hu, Y., Hajdu, I., Achar, Y.J., Izhar, L., Petit, S.A., Adamson, B., Yoon, J.C., Kowalczykowski, S.C., Livingston, D.M., Haracska, L., and Elledge, S.J. (2012)
Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress.
Mol. Cell. 47, 396-409 (published online June 14, 2012). PMID: 22704558; PMCID: PMC3613862 [Abstract] [Full Text] [PDF] [Supplemental Information]

Nimonkar, A.V., Dombrowski, C.C., Siino, J. S., Stasiak, A. Z., Stasiak, A. and Kowalczykowski, S.C. (2012)
Saccharomyces cerevisiae Dmc1 and Rad51 proteins preferentially function with Tid1 and Rad54 proteins, respectively, to promote DNA strand invasion during genetic recombination.
J. Biol. Chem., 287, 28727-28737 (published online published 29 June 2012 as 10.1074/jbc.M112.373290). PMID: 22761450; PMCID: PMC3436576 [Abstract] [Full Text] [PDF] [Supplemental Material]

Cejka, P., Plank, J.L., Dombrowski, C.C., and Kowalczykowski, S.C. (2012)
Decatenation of DNA by the S. cerevisiae Sgs1–Top3–Rmi1 and RPA complex: A mechanism for disentangling chromosomes.
Mol. Cell, 47, 886-896 (published online August 15, 2012). PMID: 22885009; PMCID: PMC3462259 [Abstract] [Full Text] [PDF] [Supplemental Information]

Morimatsu, K., Wu, Y., and Kowalczykowski, S.C. (2012)
RecFOR proteins target RecA protein to a DNA gap with either DNA or RNA at the 5' terminus: Implication for repair of stalled replication forks.
J. Biol. Chem. 287, 35621-35630 (published online 17 August 2012 as 10.1074/jbc.M112.397034). PMID: 22902627; PMCID: PMC3471720 [Abstract] [Full Text] [PDF] [Supplemental Information]

Bell, J.C., Plank, J.L., Dombrowski, C.C., and Kowalczykowski, S.C. (2012)
Direct imaging of RecA nucleation and growth on single molecules of SSB-coated ssDNA.
Nature, 491, 274-278 (published online 24 October 2012 as doi: 10.1038/nature11598). PMID: 23103864; PMCID: PMC4112059. [Abstract] [Full Text] [PDF] [Supplementary Information] [Video 1: Direct imaging of nucleation and growth of RecA on SSB-coated ssDNA] [Video 2: Optical trapping and manipulation of single molecules of gapped DNA for direct imaging of RecA^f filament assembly]
(see Nature News & Views: A glimpse of molecular competition [PDF])
(see Phys.org News: Single-DNA images give clues to breast cancer [PDF])
(see Scientific Blogging: Rad51: Watching single strands of DNA being prepped for repair could help fight breast cancer  [Printable] [PDF])
(see UC Davis News and Information: Single-DNA images give clues to breast cancer  [Video] [PDF])