Amitani,
I., Liu, B.,
Dombrowski, C.C., Baskin, R.J., and
Kowalczykowski, S.C.
(2010)
Watching individual proteins acting on single molecules of DNA.
In: Single Molecule Tools: Fluorescence Based Approaches, Part A,
Methods Enzymol., 472, Nils G. Walters, editor, Burlington: Academic
Press, 261-291
ISBN:
978-0-12-374954-3; doi: 10.1016/S0076-6879(10)72007-3. PMID:
20580968; PMCID: PMC3119597
[Abstract] [Full Text] [PDF]
Hilario,
J. and Kowalczykowski, S.C.
(2010)
Visualizing protein-DNA interactions at the single-molecule level.
Curr. Opin. Chem. Biol.,
14,
15-22. PMID: 19945909;
PMCID: PMC2819561
[Abstract]
[Full Text]
[PDF]
Kemp, M.G.,
Mason, A.C.,
Carreira, A., Reardon, J.T., Haring, S.J., Borgstahl, G.E.O.,
Kowalczykowski, S.C., Sancar, A., and Wold,
M.S. (2010)
An alternative form of replication protein A expressed in normal human tissues supports DNA
repair.
J. Biol. Chem., 285, 4788-4797 (published online 7 December 2009, as
doi:10.1074/jbc.M109.079418). PMID: 19996105;
PMCID: PMC2836084
[Abstract]
[Full Text]
[PDF]
Cejka, P.
and Kowalczykowski, S.C.
(2010)
The full-length Saccharomyces cerevisiae Sgs1 protein is a vigorous
DNA helicase that preferentially unwinds Holliday junctions.
J. Biol. Chem., 285, 8290-8301 (published online January 19, 2010, as
doi:10.1074/jbc.M109.083196). PMID: 20086270;
PMCID: PMC2832980
[Abstract]
[Full Text] [PDF]
Forget.
A.L. and Kowalczykowski, S.C.
(2010)
Single-molecule imaging brings Rad51 nucleoprotein filaments into focus.
Trends in Cell Biology, 20, 269-276 (published online
March 17, 2010, as doi:10.1016/j.tcb.2010.02.004).
PMID: 20299221;
PMCID: PMC2862779
[Abstract] [Full Text] [PDF]
(see Trends in Cell Biology - Most
Read Articles
[PDF])
Cejka, P.,
Cannavo, E., Polaczek, P., Masuda-Sasa, T., Pokharel, S., Campbell,
J.L., and Kowalczykowski, S.C.
(2010)
DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and
Mre11-Rad50-Xrs2.
Nature, 467, 112-116 (doi:
10.1038/nature09355). PMID: 20811461; PMCID: PMC3089589
[Abstract] [Full Text]
[PDF]
[Supplementary Information]
(see Egghead blog about research at UC
Davis:
DNA repair machine on the bench
[PDF])
Jensen, R.B.,
Carreira, A., and
Kowalczykowski, S.C.
(2010)
Purified human BRCA2 stimulates RAD51-mediated recombination.
Nature, 467, 678-683 (published online: August 22,
2010, doi: 10.1038/nature09399). PMID: 20729832; PMCID: PMC2952063
[Abstract] [Full Text] [PDF]
[Supplementary
Information]
(see UC Davis interview:
[Video-Flash]
[Video-MPEG4])
(see Nature News & Views:
DNA
Repair: A protein giant in its entirety [PDF])
(see Nature News:
Breast
cancer protein is finally purified
Latest News
[PDF])
(see American Cancer Society News:
New finding may unlock secrets of BRCA mutations
[PDF])
(see Biocompare, Life Sciences Articles, News:
Protein made by breast cancer gene purified
[PDF])
(see Biomedical Beat - National Institute of General Medical Sciences:
BRCA2 Breakthrough
News
[PDF])
(see Bionity.com:
Protein made by breast cancer gene purified
[PDF])
(see BioTechniques:
New gels shed light on cancer-related protein
[PDF])
(see Congressionally Directed Medical Research Programs (CDMRP), Breast
Cancer Research Highlights:
Successful isolation of BRCA2 (breast cancer type 2 susceptibility protein) and
elucidation of its mechanistic functions underlying breast cancer tumorigenesis
[PDF])
(see Davis Enterprise: Scientists dig into breast cancer origins
[PDF])
(see Deutsches Ärzteblatt:
Brustkrebs-Protein im
Labor hergestellt
[PDF])
(see e! Science News:
Protein made by breast cancer gene purified
[PDF])
(see ebiotrade:
"Nature": successfully isolated and purified human lung cancer gene BRCA2
protein
[PDF])
(see Eurekalert.org:
Protein made by breast cancer gene purified
[PDF])
(see GENNewsHighlights:
Researchers succeed in purifying protein expressed by BRCA2
[PDF])
(see GenomeWeb:
The elusive
protein, found
[PDF])
(see Guttenberg Municipal Hospital, HealthDay Daily Newsfeed:
Inner workings of gene tied to breast, ovarian cancer revealed
[PDF])
(see Higher Colleges of Technology, HCT Libraries:
BRCA2, purified, reveals some of its secrets
[PDF])
(see The Hindu:
Protein made by breast cancer gene 'purified'
[PDF])
(see Innovations Report:
Protein made by breast cancer gene purified
[PDF])
(see Journal of the National Cancer Institute:
BRCA2,
purified, reveals some of its secrets
[PDF])
(see Justmeans:
New finding may unlock secrets of BRCA mutations
[PDF])
(see Lahey Hospital and Medical Center, HealthDay News:
Inner workings of gene tied to breast, ovarian cancer revealed
[PDF])
(see Mammary Cell News:
Breast cancer protein is finally purified
[PDF])
(see MedGuru:
Pure form of tumor protein extracted successfully
[PDF])
(see Medical News Today:
Purification of
protein made by breast cancer gene
[PDF])
(see medwireNews:
Purification of BRCA2 protein allows understanding of its role in DNA repair
[PDF])
(see ModernMedicine:
Researchers isolate BRCA2 protein for first time
[PDF])
(see MSN Health and Fitness: Inner workings of
gene tied to breast, ovarian cancer revealed
[PDF])
(see Natureasia.com:
BRCA2
protein characterized
[PDF])
(see News, Chauthi Duniya:
Breast-cancer protein purified
[PDF])
(see NewScientist Health:
Fundamental breast and ovarian cancer protein isolated
[PDF])
(see Pharmaceutical Online:
Protein made by breast cancer gene purified
[PDF])
(see Santa Maria Law:
Breast
cancer research
[PDF])
(see Science Codex:
Protein made by breast cancer gene purified
[PDF])
(see ScienceDaily:
Protein
made by breast cancer gene purified
[PDF])
(see Softpedia News:
Breast cancer protein scrutinized
[PDF])
(see Synthesis, Fall/Winter 2010:
Protein made by breast cancer gene purified
[PDF])
(see Synthesis, Spring/Summer 2011:
Solving a genetic puzzle: Major findings open doors in DNA repair research
[PDF])
(see USNews Health:
Inner workings of gene tied to breast, ovarian cancer revealed
[PDF])
(see UC Davis Health System News:
Protein made
by breast cancer gene purified
[PDF])
(see UC Davis News & Information:
Protein made
by breast cancer gene purified
[PDF]
[printable])
(see WSFA 12 News Montgomery, AL: Inner workings of gene tied to
breast, ovarian cancer revealed
[PDF])
(see Yahoo! Movies India:
Breast-cancer protein purified
[PDF])
Cejka, P.,
Plank, J.L., Bachrati, C.Z., Hickson, I.D., and
Kowalczykowski, S.C.
(2010)
Rmi1 stimulates decatenation of double Holliday junctions during dissolution
by Sgs1-Top3.
Nature Struct. Mol. Biol., 17, 1377-1382 (published online
October 10, 2010; doi: 10.1038/nsmb.1919). PMID: 20935631; PMCID: PMC2988882
[Abstract]
[Full Text]
[PDF]
[Supplementary Material]
(see California Aggie:
DNA separates like a magician's rings
[PDF])
(see CheckOrphan, Research News:
DNA and the 'magic rings' trick
[PDF])
(see Davis Enterprise:
Study shows DNA acts like a 'magic rings' trick
[PDF])
(see Healthcanal:
DNA and the 'magic rings' trick
[PDF])
(see PhysOrg.com news:
DNA and the 'magic rings'
trick
[PDF])
(see UC Davis Comprehensive Cancer Center:
DNA and the
'magic rings' trick
[PDF])
(see UC Davis Health System:
DNA and the
'magic rings' trick
[PDF])
(see UC Davis News and Information:
DNA and
the 'magic rings' trick
[Printable]
[PDF])
(see UC Newsroom:
Genetic magic
trick may hold clues to Bloom's syndrome
[PDF])