Cejka, P., Vondrejs, V.,
and Storchova, Z.
(2001).
Dissection of the
functions of the Saccharomyces cerevisiae RAD6 postreplicative repair
group in mutagenesis and UV sensitivity.
Genetics.
159, 953-63. PMID:
11729144; PMCID: PMC1461873.
Cejka, P., Stojic, L.,
Mojas, N., Russell, A.M., Heinimann, K., Cannavo, E., di Pietro, M., Marra, G.,
and Jiricny, J.
(2003).
Methylation-induced G(2)/M arrest requires a full complement of the mismatch
repair protein hMLH1.
EMBO J. 22, 2245-54. PMID:
12727890; PMCID: PMC156088.
Cejka, P., Marra, G.,
Hemmerle, C., Cannavo, E., Storchova, Z.,
and Jiricny, J.
(2003).
Differential killing of mismatch
repair-deficient and -proficient cells: towards the therapy of tumors with microsatellite instability.
Cancer Res. 63, 8113-7.
PMID: 14678962.
di Pietro, M., Marra, G., Cejka,
P., Stojic, L., Menigatti, M., Cattaruzza, M.S.,
and Jiricny, J.
(2003).
Mismatch
repair-dependent transcriptome changes in human cells treated with the
methylating agent N-methyl-n'-nitro-N-nitrosoguanidine.
Cancer Res.
63, 8158-66. PMID:
14678970.
Cejka, P., Stojic, L.,
Marra, G.,
and Jiricny J. (2004).
Is mismatch repair really required for ionizing
radiation-induced DNA damage signaling?
Nat. Genet. 36, 432-3.
PMID: 15118672.
Papouli, E., Cejka, P.,
and Jiricny, J.
(2004).
Dependence of the cytotoxicity of DNA-damaging agents on the mismatch
repair status of human cells.
Cancer Res. 64, 3391-4.
PMID: 15150090.
Stojic, L., Mojas, N., Cejka, P.,
di Pietro, M., Ferrari, S., Marra, G.,
and Jiricny, J.
(2004).
Mismatch repair-dependent G2
checkpoint induced by low doses of SN1 type methylating agents requires the ATR
kinase.
Genes Dev. 18, 1331-44.
PMID: 15175264; PMCID: PMC420358.
Stojic, L., Cejka, P.,
and Jiricny, J.
(2005).
High doses of SN1 type methylating agents activate DNA damage
signaling cascades that are largely independent of mismatch repair.
Cell
Cycle 4, 473-7. PMID:
15684614.
Klasen, M., Spillmann, F.J., Marra,
G., Cejka, P.,
and Wabl, M.
(2005).
Somatic hypermutation and mismatch repair in non-B
cells.
Eur. J. Immunol. 35,
2222-9. PMID: 15940670.
Cannavo,
E., Marra, G., Sabates-Bellver, J., Menigatti, M., Lipkin, S.M., Fischer, F., Cejka, P.,
and Jiricny, J.
(2005).
Expression of the MutL homologue hMLH3 in human cells and its role in
DNA mismatch repair.
Cancer Res. 65, 10759-66.
PMID: 16322221.
Cejka, P., Mojas, N.,
Gillet, L., Schar, P.,
and Jiricny J. (2005).
Homologous recombination rescues
mismatch-repair-dependent cytotoxicity of S(N)1-type methylating agents in S.
cerevisiae.
Curr. Biol. 15, 1395-400.
PMID: 16085492.
Cejka, P.
and Kowalczykowski, S.C. (2010).
The full-length Saccharomyces cerevisiae Sgs1 protein is a vigorous
DNA helicase that preferentially unwinds Holliday junctions.
J. Biol. Chem., 285, 8290-8301 (published online January 19, 2010, as
doi:10.1074/jbc.M109.083196). PMID: 20086270;
PMCID: PMC2832980
[Abstract]
[Full Text] [PDF]
Cejka, P.,
Cannavo, E., Polaczek, P., Masuda-Sasa, T., Pokharel, S., Campbell,
J.L., and Kowalczykowski, S.C.
(2010)
DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and
Mre11-Rad50-Xrs2.
Nature, 467, 112-116 (doi:
10.1038/nature09355). PMID: 20811461; PMCID: PMC3089589
[Abstract] [Full Text]
[PDF]
[Supplementary Information]
(see Egghead blog about research at UC
Davis:
DNA repair machine on the bench
[PDF])
Cejka, P.,
Plank, J.L., Bachrati, C.Z., Hickson, I.D., and
Kowalczykowski, S.C.
(2010)
Rmi1 stimulates decatenation of double Holliday junctions during dissolution
by Sgs1-Top3.
Nature Struct. Mol. Biol., 17, 1377-1382 (published online
October 10, 2010; doi: 10.1038/nsmb.1919). PMID: 20935631; PMCID: PMC2988882
[Abstract]
[Full Text]
[PDF]
[Supplementary Material]
(see California Aggie:
DNA separates like a magician's rings
[PDF])
(see CheckOrphan, Research News:
DNA and the 'magic rings' trick
[PDF])
(see Davis Enterprise:
Study shows DNA acts like a 'magic rings' trick
[PDF])
(see Healthcanal:
DNA and the 'magic rings' trick
[PDF])
(see PhysOrg.com news:
DNA and the 'magic rings'
trick
[PDF])
(see UC Davis Comprehensive Cancer Center:
DNA and the
'magic rings' trick
[PDF])
(see UC Davis Health System:
DNA and the
'magic rings' trick
[PDF])
(see UC Davis News and Information:
DNA and
the 'magic rings' trick
[Printable]
[PDF])
(see UC Newsroom:
Genetic magic
trick may hold clues to Bloom's syndrome
[PDF])
Cejka, P.,
Plank, J.L.,
Dombrowski, C.C., and
Kowalczykowski, S.C.
(2012)
Decatenation of DNA by the S. cerevisiae Sgs1–Top3–Rmi1 and RPA
complex: A mechanism for disentangling chromosomes.
Mol. Cell, 47, 886-896 (published online August 15, 2012).
PMID:
22885009; PMCID: PMC3462259
[Abstract]
[Full Text] [PDF]
[Supplemental Information]
Cannavo, E.,
Cejka, P., and
Kowalczykowski, S.C.
(2013)
Relationship of DNA degradation by Saccharomyces cerevisiae Exonuclease 1 and
its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection.
Proc. Natl. Acad. Sci. U.S.A., 109 (published online April 15, 2013 as
doi: 10.1073/pnas.1305166110). PMID: 23589858, PMCID:
PMC3645542.
[Abstract]
[Full
Text]
[PDF]
[Supporting Information]
Paeschke, K., Bochman, M.L., Garcia, P.D., Cejka, P.,
Friedman, K.L.,
Kowalczykowski, S.C.,
and Zakian, V.A. (2013)
Pif1 family helicases suppress genome instability at G-quadruplex motifs.
Nature,
497, 458-62. (published online May 8,
2013 as doi: 10.1038/nature12149). PMID: 23657261; PMCID:
PMC3680789.
[Abstract]
[Full
Text] [PDF]
[Supplementary
Information]
(see Innovations Report:
Stability for the genome
[PDF])
(see Nature New & Views:
DNA replication: Driving past four-stranded snags
[PDF])
(see NSF
Science360 New Service
[Full Text] [PDF])
(see Universität Würzburg:
Stability for the genome
[PDF])
Bocquet, N., Bizard, A.H., Abdulrahman,
W., Larsen, N.B., Faty, M., Cavadini, S., Bunker, R.D.,
Kowalczykowski, S.C.,
Cejka, P., Hickson, I.D., and Thomä, N.H. (2014)
Structural and mechanistic insight into Holliday-junction dissolution by
topoisomerase IIIα and RMI1.
Nat. Struct. Mol. Biol., 21, 261-268. (published online February 9,
2014 as doi: 10.1038/nsmb.2775). PMID: 24509834; PMCID: PMC4292918.
[Abstract]
[Full
Text]
[PDF]
[Supplementary Text and Figures
1-6]
Fasching, C.L., Cejka, P.,
Kowalczykowski, S.C., and Heyer, W.D. (2015)
Top3-rmi1 dissolve rad51-mediated d
loops by a topoisomerase-based mechanism.
Mol. Cell. 57, 595-606 (published
online February 19, 2015 as doi:10.1016/j.molcel.2015.01.022).
PMID: 25699708; PMCID: PMC4338411.
[Abstract]
[Full Text]
[PDF]
[SupplementaI Information]